- DOCTOR’S BEST RESPIRATORY CARE – contains AP-Bio Andrographis (Andrographis paniculata) leaf extract, known as the “King of Bitters”. Indigenous to Southeast Asia and India. this bitter-tasting herbaceous plant contains a biologically significant active compound called andrographolides.*
- BOOST YOUR IMMUNITY & RESPIRATORY HEALTH – with AP-Bio Andrographis extensive clinical studies revealed Andrographis has numerous benefits to the human body supporting immune system function, respiratory, and skin health.* Andrographis, provides healthy respiratory support from nature.*
- LOADED WITH ANTIOXIDANTS – Respiratory Care helps support your body fight against free radicals and increases your immunity and overall wellness. Ensures you’re getting the essential nutrients and antioxidants that your body needs to help support respiratory health. *
- RESPIRATORY CARE INGREDIENTS – potent blend natural ingredients of Andrographis Extract 200 mg, Vitamin C 180 mg, Zinc 5.5mg – Two tablets a day helps support your immunity, upper respiratory tract health, lung health, daily energy and protection from oxidative stress.*
From the manufacturer
* This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Doctor’s Best Respiratory Care contains AP-Bio Andrographis (Andrographis paniculata) leaf extract, known as the “King of Bitters’. Indigenous to Southeast Asia and India, this bitter-tasting herbaceous plant contains a biologiy significant active compound ed andrographolides.*
Respiratory Care with Andrographis uses AP-Bio
- Immune support for respiratory & lung health*
- Helps support a healthy immune system*
- May help relieve common upper respiratory conditions*
- Contains vitamin C and Zinc
Helps Supports Respiratory Health & Well-Being
Maintain and keep your immunity strong year around with Respiratory Care contains AP-Bio Andrographis, Vitamin C and Zinc. Andrographis supports healthy lungs and helps strengthen the respiratory tract, congestion, supports overall health and well-being.* Combined supplement to boost antioxidants and protect your body, a daily dose helps give your immune system the extra support it needs to fight against seasonal colds.*
- Promotes Respiratory Health and Well-Being
- Andrographis supports healthy lungs and strengthens the respiratory tract*
Andrographis Paniculata “King of Bitters”
Andrographis paniculata is a plant that has been effectively used in traditional Asian medicines for centuries. The aerial part of the plant, used medicinally, contains a large number of chemical constituents, mainly lactones, diterpenoids, diterpene glycosides, flavonoids, and flavonoid glycosides. Controlled clinical trials its safe and effective use for reducing symptoms of upper respiratory tract infections.*
Andrographis is an annual plant, 1-3 ft high, that is one of the most commonly used plants in the traditional systems of Unani and Ayurvedic medicines. Used traditionally in , India and south-east Asia, Andrographis naturally enhances healthy immune system response.*
Superb Ingredients for Your Immune System
- Respiratory Care Ingredients –
- Andrographis Extract 200 mg, Vitamin C 180 mg, Zinc 5.5mg
- Two tablets a day helps support your immunity, upper respiratory tract health, lung health, daily energy and protection from oxidative stress.*
Vitamin C has been shown to have significant immune function. Immune cells accumulate vitamin C against a concentration gradient, with a close relationship between vitamin C supply and immune cell activity, especially phagocytosis activity and T-cell function. Accordingly, one of the consequences of vitamin C deficiency is impaired immunity, while an enhanced supply increases antibody activity and infection resistance. And there is evidence that taking vitamin C can help upper respiratory discomfort go away faster.
A scientific journal review on vitamin C notes that it contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C supports immune epithelial barrier function and promotes oxidant scavenging activity. Vitamin C accumulates in phagocytic cells, such as neutrophils, and can enhance chemotaxis, phagocytosis, and generation of reactive oxygen species. It is also needed for apoptosis and clearance of spent neutrophils from sites of infection by macrophages, thereby decreasing necrosis/NETosis and potential tissue damage. In lymphocytes vitamin C has been shown to enhance differentiation and proliferation of B- and T-cells, likely due to its gene-regulating effects. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. In turn, infections significantly impact on vitamin C levels due to metabolic requirements.
One study investigated the role of vitamin C, at concentrations equivalent to those obtained from oral intakes, on key functions of neutrophils isolated from healthy individuals. Neutrophils are a type of immune cell that is one of the first cell types to travel to the site of an infection. The study measured the effects of enhanced vitamin C uptake on the essential functions of chemotaxis, oxidant production, programmed cell death and neutrophil extracellular trap (NET) formation. Extracellular vitamin C appeared to enhance neutrophil directional mobility. Stimulation of neutrophils in the presence of vitamin C significantly increased intracellular vitamin C concentrations and NET formation was significantly attenuated. The study found that neutrophils regulate their uptake of vitamin C from the plasma of healthy humans to maintain an optimal level within the cell for proper functioning. The study concluded that oral intakes of vitamin C may help reduce tissue damage and modulate healthy NET formation.
Zinc
The essentiality of zinc in humans was established in 1963. During the past five decades, tremendous advances in both clinical and basic sciences of zinc metabolism in humans have been observed. Cell-mediated immune function is a major clinical effect of zinc in humans. Over 300 enzymes and >1000 transcription factors require zinc for their activities. Zinc is an immune cell messenger, and intracellular free zinc in these cells participate in signaling events. Zinc has been successfully used to reduce upper respiratory symptoms. Zinc not only modulates cell-mediated immunity but is also an antioxidant. Zinc supplementation in the elderly results in reduced risk of infections, decreased oxidative stress and decreased generation of cytokines.
Diets deficient in zinc lead to impaired immunity and delayed recovery from and worse outcomes following infection. Sustained insufficient zinc intake leads to dysregulation of the innate immune response and increases susceptibility to infection whereas zinc supplementation in at-risk populations has been shown to restore host defense. Upon infection, zinc deficiency leads to increased pathology due to imbalance in key signaling networks that result in excessive inflammation and collateral tissue damage. In particular, zinc impacts macrophage function, a critical front-line cell in host defense, in addition to other immune cells. Deficits in zinc adversely impact macrophage function resulting in dysregulation of phagocytosis, intracellular destroying, and cytokine production. Zinc is also critical for several transporter proteins required for proper bioredistribution of zinc within mononuclear cells to achieve an optimal immune response.
Andrographis